Definition: Smallpox is a disease that was first reported in 1876 in Kansas. The causative agent of Smallpox, vaccinia virus, has since spread to many countries worldwide, including the United States. In recent years, vaccination for smallpox has been recommended as an effective strategy against Smallpox. Mpox (Vaccinia) Vaccine, Live is a vaccine that was developed in 2015 and is made up of two parts: a live attenuated (attacked by virus) vaccine and a weakened or inactivated (not attacked by virus) vaccine. The live attenuated vaccine contains the original virus of Smallpox, while the weakened or inactivated vaccine contains only the nonviral components. This allows the immune system to recognize and fight the virus rather than be infected. The live attenuated vaccine is designed to stimulate the body's own antibodies to fight the virus. This immune response can lead to recovery from smallpox. The weakened or inactivated vaccine is used when the body has already been infected by the original virus, but not yet developed immunity. In this case, the vaccine provides a partial immune response against the virus. It should be noted that vaccines are not 100% effective and can still cause serious side effects such as fever, headaches, fatigue, or rashes in some cases. It is important to get vaccinated promptly when it becomes available to protect yourself and others from smallpox.
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